Table 2.
Study | Followup (years) for primary clinical outcome | Participants evaluated clinically | Participants evaluated arthroscopically | Participants evaluated histologically | Cointerventions | CPM | Time to partial weightbearing | Time to full weightbearing |
---|---|---|---|---|---|---|---|---|
Gudas et al. [19] | 3 | 57 (95%) | 34 (57%)* | 25 (42%)* | None | No | 4 weeks | 8 weeks |
Bartlett et al. [1] | 1 | 91 (100%) | 42 (46%) | 25 (27%) | None | No | 1 day | 10 days |
Knutsen et al. [29] | 2 | 80 (100%) | 77 (96%) | 67 (84%) | None | Yes | 1 day | 8–12 weeks |
Visna et al. [45] | 1 | 50 (100%) | 4 (8%)† | 4 (8%)† | 22 (MACI group) 19 (abrasion group) | NR | 3 weeks | 6–8 weeks |
Bentley et al. [2] | 1 | 100 (100%) | 60 (60%)‡ | 19 (19%)§ | NR | No | NA | 1 day |
Horas et al. [24] | 2 | 40 (100%) | 12 (30%)* | 11 (28%)* | None | Yes | 2 weeks | 12 weeks |
*Nonrandom selection of patients to evaluate arthroscopically and biopsy; †all from MACI group; ‡64% of patients with ACI and 55% of patients with OAT; §all from ACI groups; CPM = continuous passive motion; NR = not reported; NA = not applicable; MACI = matrix-induced autologous chondrocyte implantation; ACI = autologous chondrocyte implantation; OAT = osteochondral autograft transplant.