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. Author manuscript; available in PMC: 2008 Aug 11.
Published in final edited form as: Med Image Comput Comput Assist Interv. 2006;9(Pt 2):561–568. doi: 10.1007/11866763_69

Fig. 2.

Fig. 2

Two examples of tumor volume reduction in which vessel MP values correctly presaged tumor activity. In both graphs, the x axis gives time in months (time 0 is the baseline scan prior to treatment). The y axis gives a percentage (0–100%) representing both the malignancy probability (black bar) and the tumor percent volume (grey bar) in which the numerator is the tumor volume and the denominator the maximum tumor volume recorded for that patient; the tumor volume is 100% at the time point it was largest during the study. Left: Case 015. The tumor regressed significantly at month 2 but subsequently enlarged rapidly; vessel MP correctly flagged the tumor as of high (100%) MP at month 2, presaging worsening during the next cycle. Right: Case 003. The tumor volume progressively regressed between months 0 and 4 with vessel MP indicating a drop in activity from 100% to 64% at month 2, correctly presaging future improvement during the next 2-month cycle. MP returned to 100% at month 4 at which time the tumor stopped regressing; the subject also developed carcinomatous meningitis. No MRA data were available after month 4.