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. Author manuscript; available in PMC: 2008 Aug 11.
Published in final edited form as: J Clin Oncol. 2008 Aug 1;26(22):3749–3755. doi: 10.1200/JCO.2007.14.3974

Table 1.

Ototoxicity Grading Criteria

GRADE 1: 40 dB HL loss at 6000 and/or 8000 Hz
GRADE 2: > 25 dB HL loss at 3000 and/or 4000 Hz
GRADE 3*: > 25 dB HL loss at 2000 Hz
GRADE 4*: ≥ 40 dB HL loss at 2000 Hz

A loss is defined as a change from baseline at any one frequency

*

Patient requires hearing aids