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. Author manuscript; available in PMC: 2008 Aug 11.
Published in final edited form as: Phys Rev Lett. 2008 May 6;100(18):180602. doi: 10.1103/PhysRevLett.100.180602

FIG. 1.

FIG. 1

(Color online) Comparison of ΔFt estimators: Jarzynski’s equality applied to 500 forward (rightward triangles) or reverse pullings (leftward triangles, time reversed so that ΔFt = ΔF at t = 0.75); our optimized estimator, Eq. (7) (upward triangles) and Eq. (16) of Ref. [26] (dotted line) applied to 250 pullings in each direction. The exact ΔFt, calculated by applying Gauss-Kronrod quadrature in MATLAB 7.5 to numerically integrate ∫e−βH(z;t)dz between z̄(t) −5 < z < z̄(t) + 5, is shown as a shaded line.