Fig. 2.
Inhibition of Kir1.1 and Kir3.1/3.4 by TPN derivatives. Currents of Kir1.1 (A, C, and E) and Kir3.1/3.4 (B, D, and F) elicited with the voltage protocol shown, in the absence or presence of TPNQ or it derivatives. All leak currents were obtained after adding TPNQ at concentrations >100 times the Kd value. Dashed lines indicate the zero current levels.