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Analysis of Kir1.1 and Kir31./3.4 inhibition by TPN derivatives. Fraction of Kir1.1 (A) or Kir3.1/3.4 (B) current remaining (mean ± SEM., n = 5) plotted against the toxin concentration. The curves through the data are fits of the equation I/Io = Kd/(Kd + [toxin]).