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. 2008 Aug 15;283(33):22649–22658. doi: 10.1074/jbc.M802426200

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Copyright © 2008, The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 6. — ZnPy effects on the heteromultimeric KCNQ1-KCNE3 channels. A and B show the currents induced by KCNQ1 and heteromultimeric KCNQ1-KCNE3. Compared with the KCNQ1 homomultimer currents, coexpression with KCNE3 caused a constitutively active current. C, the currents recorded in the same cells in B after application of 10 μm ZnPy are shown. D, the histogram shows the effects of 10 and 20 μm ZnPy on KCNQ1-KCNE3 heteromultimers. E, the I-V relationship of KCNQ1-KCNE3 in the absence or presence of 10 or 20 μm ZnPy is shown.