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The application of the water-soluble polymer to a cortical defect significantly decreased the rate of osteomyelitis formation (p ≤ 0.004) and rates of positive cultures (p ≤ 0.02) compared with bone wax. There was no difference between the polymer group and the untreated control group in the rates of osteomyelitis, positive cultures, or healing of bone defects (p ≤ 0.001).
