Table 5.

Multivariate analysis of selected clinical factors in patients with skeletal metastasis of lung cancer

Prognostic factor	p Value	Hazard ratio (95% confidence interval)
Positive
Gender (female)	0.63	1.13 (0.68–1.88)
Performance status (0, 1)	0.09	1.69 (0.93–3.08)
Adenocarcinoma	< 0.01	2.17 (1.30–3.62)
Pathologic fracture	0.33	1.39 (0.71–2.73)
Chemotherapy	0.53	1.20 (0.68–2.11)
Gefitinib	0.03	2.42 (1.09–5.32)
Negative
Multiple bone metastasis	0.14	1.68 (0.84–3.34)
Appendicular bone metastasis	0.01	2.05 (1.18–3.56)