Figure 2.

Stereological analysis of total numbers of pyramidal neurons in hippocampal area CA1 and quantification of hippocampal volume. (A) Cresyl violet-stained horizontal section of hippocampus from c-rel^−/− and wild-type littermate mice were compared for the possible presence of gross morphological changes in c-rel^−/− mice. We found no gross morphological changes or differences in the hippocampus between c-rel^−/− and wild-type littermate mice. Total hippocampal volume (B) and CA1 pyramidal neuron number (C) were determined from horizontal cresyl violet sections. The hippocampal volume and CA1 neuron numbers were not different between c-rel^−/− and wild-type littermate mice. n = 3 wild-type and 3 c-rel^−/− (male only). Scale bars, 100 μm.