Table 1.

Maturation Stage, before and after 48 hours of culture, and results of in vitro fertilization of oocytes collected from control and PDE3 inhibitor-treated monkeys during COv protocols.

	Oocyte Stage
	Initial	24 h	48 h	Normal Fertilization
ORG 9935	GV	M1	0PB/1PN	No
	GV	GV	GV	No
	GV	M1	M1	No
	GV	GV	GV	No
	GV	M1	M1	No
	M1	1PB/0PN	Fragmented	No
Control	M1	M1	ATR	No
	M2	2PB/2PN	4 cell	Yes
	M1	2PB/2PN	Fragmented	Yes

GV = germinal vesicle intact; M1 = metaphase 1; M2 = metaphase 2; PB = polar body; PN= pronucleus; ATR= atretic