Vertical migration of granular layer-restricted β-galactosidase expression in tail epidermis of CMV-Cre-ERT/ACZL double heterozygous mice. Two series of daily tamoxifen injection, from day 0 to 4 and from day 25 to 29, were administered to 6- to 8-week-old CMV-Cre-ERT/ACZL double heterozygous mice. Tail biopsies were collected just before the first tamoxifen injection (DAY 0, a) and at different days after the first injection, as indicated (b–f). BM arrows, B, S, G, and C are as defined in legend to Fig. 3. (Bar = 25 μm.)