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. 2008 Aug 20;3(8):e3013. doi: 10.1371/journal.pone.0003013

Table 5. Associations of C-reactive Protein (CRP) with Carotid Intima-media Thickness (CIMT) Obtained from the Instrumental Variables Analysis in Which CRP Haplotypes Act as An Instrument for the Non-confounded and Unbiased Effect of CRP.

Exposure N Age and Sex Adjusted Beta (95% CI) for CIMT (mm) at Mean Age of 61.0 Years
Per doubling of CRP concentration at mean age 61.0 3299 −0.005 (−0.031 to 0.021) P = 0.71
Per doubling of CRP concentration at mean age 49.2 3016 −0.001 (−0.025 to 0.023) P = 0.94