Table 1.
Five Traditional Medicines in Clinical Trials
| Clinical Trials |
|||
|---|---|---|---|
| Compound | Disease | Number | Principal Sponsors |
| Artemisinin | Malaria | 81 | 31 charities, institutes, universities, and companies based in Australia, Austria, Belgium, Colombia, Ethiopia, France, Gambia, Germany, Ghana, Guinea-Bissau, the Netherlands, Papua New Guinea, South Africa, Sudan, Sweden, Switzerland, the United Kingdom, and the USA; and working in numerous Asian, African, and South American locations |
| Cytomegalovirus infection | 1 | Hadassah Medical Organization, Israel | |
| Schistosomiasis | 1 | Dafra Pharma, Belgium | |
| Triptolide & Celastrol (T. wilfordii extract) | Rheumatoid arthritis | 1 | National Institute of Arthritis and Musculoskeletal and Skin Diseases, MD, USA |
| Capsaicin | Chronic pain | 13 | NeurogesX, CA, USA; AlgoRx Pharmaceuticals, NJ, USA |
| Postoperative pain | 5 | National Institute of Dental and Craniofacial Research, MD, USA; AlgoRx Pharmaceuticals, NJ, USA | |
| Radiation-induced mucositis | 1 | North Central Cancer Treatment Group, MN, USA | |
| Alopecia areata | 1 | University of Minnesota | |
| Morton’s neuroma | 1 | AlgoRx Pharmaceuticals | |
| Osteoarthritis | 1 | Khon Kaen University | |
| Interstitial cystitis | 1 | National Institute of Diabetes and Digestive and Kidney Diseases,MD,USA | |
| Curcumin | Colon cancer | 6 | Chao Family Comprehensive Cancer Center, CA, USA; Tel-Aviv Sourasky Medical Center, Israel; Johns Hopkins University, MD, USA; University of Michigan Comprehensive Cancer Center, USA; University of Pennsylvania, USA; University of Medicine and Dentistry, NJ, USA |
| Pancreatic cancer | 3 | Rambam Medical Center, Israel; M.D. Anderson Cancer Center, TX, USA; Tel-Aviv Sourasky Medical Center, Israel | |
| Alzheimer’s disease | 2 | John Douglas French Foundation, CA, USA; Chinese University of Hong Kong | |
| Chemotherapy-induced mucositis | 1 | Hadassah Medical Organization, Israel | |
| Multiple myeloma | 1 | M.D. Anderson Cancer Center,TX,USA | |
| Psoriasis | 1 | University of Pennsylvania,USA | |
| Cystic fibrosis | 1 | Seer Pharmaceuticals,CT,USA | |
Includes registered, open, closed, terminated, and completed trials of these compounds, parent extracts, or derivatives. For details see www.clinicaltrials.gov. Data current as of August 21, 2007.