Abstract
The lymphoproliferative disease virus of turkeys was molecularly cloned, structurally mapped, and shown to represent a distinct class of retroviruses evolutionarily related to the avian leukemia-sarcoma virus group. The cloned provirus did not contain any known oncogene or other cellularly derived sequences and was established as a replication-competent oncogenic entity capable of inducing the disease in the absence of any associated transforming counterpart.
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- Chisholm O., Symonds G. Transfection of myeloid cell lines using polybrene/DMSO. Nucleic Acids Res. 1988 Mar 25;16(5):2352–2352. doi: 10.1093/nar/16.5.2352. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DeLorbe W. J., Luciw P. A., Goodman H. M., Varmus H. E., Bishop J. M. Molecular cloning and characterization of avian sarcoma virus circular DNA molecules. J Virol. 1980 Oct;36(1):50–61. doi: 10.1128/jvi.36.1.50-61.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gazit A., Schwarzbard Z., Yaniv A., Ianconescu M., Perk K., Zimber A. Organotropism of the lymphoproliferative disease virus (LPDV) of turkeys. Int J Cancer. 1982 May 15;29(5):599–604. doi: 10.1002/ijc.2910290518. [DOI] [PubMed] [Google Scholar]
- Gazit A., Yaniv A., Ianconescu M., Perk K., Aizenberg B., Zimber A. Molecular evidence for a type C retrovirus etiology of the lymphoproliferative disease of turkeys. J Virol. 1979 Sep;31(3):639–644. doi: 10.1128/jvi.31.3.639-644.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gazit A., Yaniv A., Ilani A., Ianconescu M., Perk K., Zimber A. Genetic control of the organ specificity of lymphoproliferative disease virus (LPDV) of turkeys. Int J Cancer. 1983 Mar 15;31(3):351–356. doi: 10.1002/ijc.2910310316. [DOI] [PubMed] [Google Scholar]
- Kawai S., Nishizawa M. New procedure for DNA transfection with polycation and dimethyl sulfoxide. Mol Cell Biol. 1984 Jun;4(6):1172–1174. doi: 10.1128/mcb.4.6.1172. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Oi V. T., Morrison S. L., Herzenberg L. A., Berg P. Immunoglobulin gene expression in transformed lymphoid cells. Proc Natl Acad Sci U S A. 1983 Feb;80(3):825–829. doi: 10.1073/pnas.80.3.825. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Perk K., Ianconescu M., Yaniv A., Zimber A. Morphologic characterization of proliferative cells and virus particles in turkeys with lymphoproliferative disease. J Natl Cancer Inst. 1979 Jun;62(6):1483–1487. [PubMed] [Google Scholar]
- Reddy E. P., Reynolds R. K., Watson D. K., Schultz R. A., Lautenberger J., Papas T. S. Nucleotide sequence analysis of the proviral genome of avian myelocytomatosis virus (MC29). Proc Natl Acad Sci U S A. 1983 May;80(9):2500–2504. doi: 10.1073/pnas.80.9.2500. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Southern E. M. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol. 1975 Nov 5;98(3):503–517. doi: 10.1016/s0022-2836(75)80083-0. [DOI] [PubMed] [Google Scholar]
- Taylor J. M., Illmensee R., Summers J. Efficeint transcription of RNA into DNA by avian sarcoma virus polymerase. Biochim Biophys Acta. 1976 Sep 6;442(3):324–330. doi: 10.1016/0005-2787(76)90307-5. [DOI] [PubMed] [Google Scholar]
- Yaniv A., Gazit A., Ianconescu M., Perk K., Aizenberg B., Zimber A. Biochemical characterization of the type C retrovirus associated with lymphoproliferative disease of turkeys. J Virol. 1979 Apr;30(1):351–357. doi: 10.1128/jvi.30.1.351-357.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]