Figure 3.

Targets expressing high levels of HLA-G are protected from lysis by NK clones and a NK tumor line. NK clones that were prepared from donor MM and the NK tumor line YTS were incubated with various [³⁵S]methionine-labeled target cells for 5 hr at E:T ratio of 1:1 for the clones and 5:1 for the tumor line. One out of three representative experiments is shown. The level of HLA-G expression correlates with the turnover of MHC class I proteins at the cell surface.