Table 1.

Parameter values used for xenon injection model

Parameter	Value
Vi	5 ml
Ti	3 s
I	8.7 mM*
k1	[0.00917 s−1]†
P	4.9 ml/s‡
λ	1§
T1sXe	16 s¶
T1Xe	30 s‖
Td	2 s

^*Estimated from the relative solubility of xenon in the Intralipid emulsion (19), and assuming a 5-atm equilibrium xenon overpressure, an initial xenon polarization of 0.1, and 100% isotopic labeling. 

^†From a brain blood flow rate of 52.9 ml/min per 100 g (ref. 29), a brain mass of 1,400 g, and a specific gravity of 1.04 (ref. 34). 

^‡Estimated as the total volume of blood per second supplied by one carotid artery, given the value for k₁. 

^§Effective value estimated from those of white and gray matter given in ref. 35 (in vitro data from dogs). 

^¶From ref. 19. 

^‖From ¶ footnotes in text, in rat brain.