Table 4.
Indices of severity of malaria and mortality according to genotype for α+-thalassemia in 433 children admitted to the hospital with malaria
| −α/−α | αα/−α | αα/αα | P value | |
|---|---|---|---|---|
| Hb, g/dl | 6.5 (1.4–13.4) | 5.2 (2.3–16.6) | 5.8 (2.4–13.9) | 0.097 |
| [202] | [146] | [85] | ||
| Glucose, mmol/liter | 4.9 (1.0–10.1) | 4.8 (1.0–12.4) | 5.1 (2.1–14.6) | 0.54 |
| [193] | [135] | [84] | ||
| Bicarbonate, mmol/liter | 20 (8–33) | 21 (9–35) | 21 (7–31) | 0.57 |
| [191] | [131] | [83] | ||
| Lactate, mmol/liter | 3.1 (1.2–15.6) | 2.9 (1.4–11.1) | 2.7 (1.4–8.9) | 0.53 |
| [188] | [135] | [80] | ||
| P. falciparum, log10 value/μl | 4.4 (1.4–5.9) | 4.3 (1.5–5.8) | 4.1 (1.8–5.7) | 0.33 |
| [196] | [140] | [81] | ||
| Coma | 32/197 (16.2) | 24/144 (16.7) | 7/85 (8.2) | 0.16 |
| Deaths | 9/202 (4.5) | 6/146 (4.1) | 0/85 (0) | 0.15 |
For coma and deaths, percentages are shown in brackets and analysis is χ2 test for trend. For other variables, median values with inter-quartile range in brackets and number of observations in square brackets are shown, and analysis is by Kruskal–Wallis test.