Figure 1.

Combination indices of gemcitabine and oxaliplatin. Panc-1 cells were treated with various concentrations of gemcitabine or oxaliplatin at a fixed ratio of 1 gemcitabine to 10 oxaliplatin according to schedule 1 or 2. The combination indices were then calculated as described in the Materials and Methods section at surviving fractions between 0.5 and 0.01. Data are the mean of n = 3 to 5 independent experiments.