Figure 4.

The effects of gemcitabine and oxaliplatin on γ-H2AX in response to radiation. (A) BxPC-3 or (B) Panc-1 cells were treated with gemcitabine (0.3 or 1 µ M, respectively) or oxaliplatin (3 or 10 µM, respectively) according to treatment schedule 1. At the end of the treatment schedule, cells were treated with 8-Gy radiation. Twenty-four hours postirradiation, cells were analyzed for γ-H2AX by immunoblot analysis. Data are shown are from a single experiment representative of three independent experiments.