Table 1.
Sites of incorporation of grafted SVZ cells
| Mother no.-mouse no. (age) | OB | Ctx | St | Hp | Sep | Th | HTh | SC | IC | Md | Cb |
|---|---|---|---|---|---|---|---|---|---|---|---|
| X::LacZ SVZ transplants | |||||||||||
| 3-1 (P12) | ND | ND | ND | ND | ND | ND | ND | − | +++ | ND | ND |
| 3-2 (P12) | +++ | − | − | − | +++ | +++ | ++ | − | ++++ | +++ | − |
| (gcl) | |||||||||||
| 3-3 (P12) | − | − | − | − | − | ++ | +++ | − | +++ | ++ | + |
| (MB, LH) | |||||||||||
| NSE::LacZ SVZ transplants | |||||||||||
| 9-1 (P1) | + | ND | ND | ND | ND | + | ++ | ND | +++ | ND | ND |
| (gcl) | |||||||||||
| 1-2 (P8) | ++ | − | − | − | ++ | + | +++ | − | +++ | − | − |
| (gcl) | (MB) | ||||||||||
| 2-2 (P9) | ++ | − | − | − | − | − | − | ++++ | ++ | − | − |
| (gcl) | |||||||||||
| 2-5 (P11) | ++ | − | − | − | − | − | +++ | − | ++++ | − | − |
| (gcl) | (MB) | ||||||||||
| 2-6 (P11) | ++ | − | − | − | ++ | ++++ | +++ | − | ++++ | − | ++ |
| (gcl) | |||||||||||
| 4-3 (P11) | +++ | − | ND | ND | ND | ND | ND | − | ++++ | − | ND |
| (gl, gcl) | |||||||||||
| 4-4 (P11) | ++ | − | − | − | − | ++ | + | − | ++++ | − | ++ |
| (gcl) | (MB) | ||||||||||
| 1-7 (P12) | + | − | − | − | − | − | − | + | + | − | − |
| (gcl) | |||||||||||
| 1-6 (P12) | ++ | − | − | − | − | + | − | − | − | − | − |
| (gcl) | |||||||||||
| 1-5 (P12) | +++ | − | − | − | +++ | +++ | +++ | − | ++++ | − | +++ |
| (gl, gcl) | (MB, VM) | ||||||||||
| 4-5 (P36) | + | − | − | − | − | − | − | − | − | − | + |
| (gcl) | |||||||||||
| 4-6 (P36) | ++ | − | − | − | − | − | − | − | + | − | − |
| (gcl) | |||||||||||
| 4-7 (P36) | ++++ | − | ++ | − | − | + | + | − | ++ | − | − |
| (gl, gcl) | |||||||||||
| 4-8 (P36) | ++ | − | − | − | − | ++ | − | − | ++ | − | − |
| (gcl) | |||||||||||
| 4-9 (P36) | + | − | − | − | − | − | ++ | − | − | − | − |
| (gl) | (VM) |
Distribution of β-galactosidase positive cellular incorporation after transplantation of LacZ marked SVZ cells to the forebrain ventricle of E15 embryos. Brains were examined as horizontal sections. ++++, >500 positive cells; +++, >100 positive cells; ++, >10 positive cells; +, 1-10 positive cells; −, no detectable staining; ND, not determined. OB, olfactory bulb; Ctx, cortex; St, striatum; Hp, hippocampus; Sep, septum; Th, thalamus; HTh, hypothalamus; SC, superior colliculus; IC, inferior colliculus; Md, medulla; Cb, cerebellum; gcl, granule cell layer; gl, periglomerular cell layer; MB, mamillary body; LH, lateral hypothalamic nucleus; VM, ventromedial hypothalamic nucleus.