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Paired-pulse modulation of macroscopic currents. (A) PPR plotted against interpulse interval, from 5 to 500 msec (each point is the mean ± SEM for 20–64 trials). (Inset) Sample traces from macroscopic current experiment. Shown (from top to bottom) are responses to paired pulses with interpulse interpulse intervals of 7, 19, and 50 msec, respectively. (B) Same plot as in A, with the x axis expanded to show detail at short time intervals.
