Table 1.

Effects of OFQ on forced motor performance in mice

	Mice with motor impairment
	Proportion	Percent
OFQ (i.c.v.)
Vehicle	0/10	0
0.1 nmol	0/20	0 NS
0.3 nmol	0/20	0 NS
1 nmol	5/20	25 NS
3 nmol	5/10	50 NS
Diazepam (p.o.)
Vehicle	0/10	0
1 nmol/kg	0/10	0 NS
3 nmol/kg	0/10	0 NS
10 nmol/kg	3/10	30 NS
30 nmol/kg	8/10	80†

Motor performance was measured in a traction test as described. NS, not significant. 

^†P < 0.05, Fisher exact probability test.