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. 2008 Aug 20;3(8):e3017. doi: 10.1371/journal.pone.0003017

Figure 5. Electrophoretic analysis and differential sensitivity to proteolysis of PrPres in different MM2 CJD patients.

Figure 5

PrPres from human brain homogenates (MM2 or MV2 subtypes of sCJD) and from primate experimentally infected with BASE were purified under high concentrations of proteinase K, and detected with monoclonal antibodies that recognize either the core (3F4, Panel A) or the octapeptide region (Panel B) of the protein.