Table 2.
Summary of consistent amino acid change among the five DENV-2 genotypes viruses.
| PROTEIN | AMINO ACID POSITIONSa | |||||||||||||
| C and PrM | 101 | 104 | 106 | 108 | 112 | 129 | 130 | 142 | 143 | 145 | 153 | |||
| PrM | 14 | 15 | 28 | 29 | 31 | 39 | ||||||||
| STRAIN/YEAR | ACCESSION GENBANK No. | DIAGNOSIS | GENOTYPE | |||||||||||
| Tonga/74 | AY744147 | DF | AMERICAN | T | M | I | L | V | S | R | K | D | T | M |
| S1vaccine/USA/93 | M19197 | DF | AMERICAN | T | M | I | L | V | S | R | K | D | T | M |
| 131/MEX/92 | AF100469 | DF | AMERICAN | T | M | I | L | V | S | R | K | D | T | M |
| I348600/COL/86 | AY702040 | DF | AMERICAN | T | M | I | L | V | S | R | K | D | T | M |
| P23085 INDI-60/01 | DQ448238 | DF | AMERICAN | T | M | I | L | V | S | R | K | D | T | M |
| Ven2/87 | AF100465 | DF | AMERICAN | T | M | I | L | V | S | R | K | D | T | L |
| HUAT2/MEX/01 | AY692469 | DF | ASIAN/AMERICAN | T | V | I | L | A | G | R | K | V | V | L |
| SALC9/MEX/01 | AY692465 | DF | ASIAN/AMERICAN | T | V | I | L | A | G | R | K | D | V | I |
| HUAT11/MEX/01 | AY692470 | DHF | ASIAN/AMERICAN | T | V | I | L | A | G | R | K | D | V | I |
| HUAT12/MEX/01 | AY692471 | DF | ASIAN/AMERICAN | T | V | I | L | A | G | R | E | D | V | I |
| TUX19/MEX/01 | AY692467 | DHF | ASIAN/AMERICAN | T | V | I | L | A | G | R | E | D | V | I |
| TON4/MEX/01 | AY692468 | DHF | ASIAN/AMERICAN | T | V | I | L | A | G | R | E | D | V | I |
| JUCH5/MEX/01 | AY692466 | DHF | ASIAN/AMERICAN | T | V | I | L | A | G | R | E | D | V | I |
| OAX/MEXS707/05* | EF595822 | DF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | M |
| OAX/MEXS1038/05* | EF595828 | DF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| OAXS1656/MEX/05* | EF595834 | DF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| OAX/MEXS739/05* | EF595829 | DF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| OAX/MEXS1733/06* | EF595821 | DF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| OAX/MEXS14946/06* | EF595800 | DHF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| OAX/MEXS14760/06* | EF595824 | DHF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| OAX/MEXS1020/06* | EF595823 | DHF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| VER/MEXS013A/06* | EU552535 | DHF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| VER/MEXS011A/06* | EU552536 | DHF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| VER/MEXS008A/06* | EU552538 | DHF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| VER/MEXS015A/06* | EU552534 | DF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| VER/MEXS033A/06* | EU552537 | DF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| VER/MEXS020A/O6* | EU552539 | DF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| Cuba13/97 | AY702034 | DF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| Cuba115/97 | AY702036 | DF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| Cuba205/97 | AY702039 | DSS | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| Cuba165/97 | AY702038 | DHF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| Cuba58/97 | AY702035 | DF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| Cuba89/97 | AY702037 | DHF/DSS | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| MART/98-703/98 | AF208496 | DF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| DR23/01 | AB122020 | DF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| DR31/01 | AB122021 | DF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| DR59/01 | AB122022 | DHF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| LARD1701/Ven/01 | AF360861 | DF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| LARD1432/Ven/01 | AF360860 | DF | ASIAN/AMERICAN | T | V | V | L | A | G | R | E | D | V | I |
| LARD1910/Ven/01 | AF360862 | DF | ASIAN/AMERICAN | T | V | I | L | A | G | R | E | D | V | I |
| LARD1996/Ven/01 | AF360863 | DF | ASIAN/AMERICAN | T | V | I | L | A | G | R | E | D | V | I |
| Mara3/Ven/02 | AY0444421 | DHF | ASIAN/AMERICAN | T | V | I | L | A | G | R | E | D | V | I |
| BR64022/02 | AF489932 | NA | ASIAN/AMERICAN | T | V | I | L | A | G | R | E | D | V | I |
| Jamaica/1409/83 | M20558 | DHF | ASIAN/AMERICAN | T | V | I | L | A | G | R | E | D | V | I |
| China 04 | U87411 | DHF | ASIAN/AMERICAN | T | V | I | L | A | G | R | E | D | V | I |
| CO390/Th/99 | AF100462 | DHF | ASIAN 1 | S | V | I | L | V | S | R | E | D | V | M |
| Bangkok 1974 | AJ487271 | NA | ASIAN 1 | S | M | I | L | V | S | R | E | D | V | M |
| 16681/USA/97 | U87411 | NA | ASIAN 1 | S | M | I | L | V | S | R | E | V | V | M |
| PDK53/USA/97 | U87412 | NA | ASIAN 1 | S | M | I | L | V | S | R | E | V | V | M |
| 16681-PDK53/97 | U87411 | DHF | ASIAN 1 | S | M | I | L | V | S | R | E | D | V | M |
| ThNH-p11/93 | AF022437 | DF | ASIAN 1 | S | M | I | L | V | S | R | E | D | V | M |
| ThNH-p12/93 | AF022438 | DF | ASIAN 1 | S | M | I | L | V | S | R | E | D | V | M |
| ThNH-p14/93 | AF022439 | DHF | ASIAN 1 | S | M | I | L | V | S | R | E | D | V | M |
| ThNH-7/93 | AF022434 | DSS | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| ThNH-28/93 | AF022435 | DHF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| ThNH-52/93 | AF022436 | DHF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| ThNH-p16/93 | AF022440 | DF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| ThNH-p36/93 | AF022441 | DHF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| ThNH29/93 | AF169678 | DHF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| ThNH36/93 | AF169679 | DF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| ThNH45/93 | AF169680 | DHF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| ThNH55/93 | AF169681 | DHF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| ThNH54/93 | AF169682 | DHF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| ThNH62/93 | AF169683 | DHF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| ThNH63/93 | AF169684 | DHF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| ThNH69/93 | AF169685 | DHF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| ThNH73/93 | AF169686 | DHF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| ThNH76/93 | AF169687 | DHF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| ThNH81/93 | AF169688 | DHF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| Mara 4/Ven/90& | AF100466 | DHF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| K0008/Th/99 | AF100459 | DHF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| K0010/Th/99 | AF100460 | DF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| C0371/Th/99 | AF100461 | DF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| C0166/Th/99 | AF100463 | DF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| C0167/Th/99 | AF100464 | DHF | ASIAN 1 | S | M | I | L | V | S | I | E | D | V | M |
| New Guinea C/44 | D00346 | DHF | ASIAN 2 | T | M | I | L | V | S | R | E | D | V | M |
| 43/China/89 | AF204178 | DF | ASIAN 2 | T | M | I | L | V | S | R | G | D | V | M |
| 44/China/87 | AF204177 | DF | ASIAN 2 | T | M | I | L | V | S | R | G | D | V | M |
| BA05i/Indon/05 | AY858035 | DF | COSMOPOLITAN | T | I | I | M | V | S | R | E | N | V | M |
| TSV01/Austra/93 | AY037116 | NA | COSMOPOLITAN | T | I | I | M | V | S | R | E | N | V | M |
| 98900666/Indo/04 | AB189124 | DSS | COSMOPOLITAN | T | V | I | M | V | S | R | E | N | V | M |
| ZS01/China/01 | EF051521 | NA | COSMOPOLITAN | T | V | I | M | V | S | R | E | N | V | M |
| GWL18/INDI/01 | DQ448231 | NA | COSMOPOLITAN | T | V | I | L | A | S | R | E | D | V | M |
| GWL39/INDI/01 | DQ448232 | NA | COSMOPOLITAN | T | V | I | L | A | S | R | E | D | V | M |
aAmino acid sequence was numbered starting from protein C or prM to the end of the last codon sequenced. *Sequences of this study.
&Recombinant strain [16].