FIGURE 11.
Sequence alignment of TviB and its homologues: WbpA, an UDP-GlcNAc 6-dehydrogenase from Pseudomonas aeruginosa PAO1 (31% identity, 52% similarity),16 WbpO, an UDP-GalNAc 6-dehydrogenase from Pseudomonas aeruginosa PAO1 (65% identity, 83% similarity).15 Also included is the sequence of UDP-Glucose dehydrogenease from Group A Streptococci.12 The six cysteine residues in TviB are highlighted in bold phase. Cys261 (TviB sequence number), which is conserved among all four sequences, is marked with an asterisk.