Table 2.
Evaluation of blood stream infections.
| Item | Group 1 (heparin) |
Group 2 (TauroLock™) |
P value |
| No. of BSI events | 30 | 25 | |
| No. (%) of patients with at least 1 BSI | 24 (27) | 21 (24) | 0.74 |
| No. (%) of BSI with CoNS* or MRSE§ | 14 (47) | 3 (11) | 0.004 |
| CoNS: 4 (13) | CoNS: 3 (11) | ||
| MRSE: 10 (33) | MRSE: 0 (0) | ||
| Incidence density‡ for All BSI events (CI95) | 4.93 (3.33–7.04) | 3.82 (2.52–5.56) | 0.35 |
| Incidence density‡ calculated with the number of specific isolates | |||
| BSI with CoNS/MRSE | 2.30 (1.26–3.86) | 0.45 (0.09–1.31) | 0.004 |
| BSI other Gram positive | 0.66 (0.18–1.68) | 1.19 (0.52–2.35) | 0.32 |
| BSI E. coli | 0.66 (0.18–1.68) | 1.49 (0.72–2.74) | 0.15 |
| BSI all Gram negative | 1,97 (1.02–3.44) | 2.24 (1.25–3.69) | 0.74 |
Group 1 = heparin (2004–2005) vs. group 2 = TauroLock™ (2005–2006)
* CoNS = coagulase-negative Staphylococci (methicillin-sensitive)
§MRSE = methicillin-resistant coagulase-negative Staphylococci
+ The percentage refers to all documented BSI in this group (100%).
‡ The ID refers to the number of events per 1000 inpatient CVAD utilization days.
Δ IQR = interquartile range, 25–75. Percentile