Table 1.
Clinical and metabolic characteristics of the subjects as a function of the diagnosis of MS based on the NCEP-ATPIII criteria
TOTAL (n = 720) | Metabolic Syndrome (NCEP) | P | ||
No (n = 510) | Yes (n = 210) | |||
Females | 60.6(436) | 51.4(262) | 82.8(174) | < 0.001 |
Age;years | 66.9(SD = 10.9) | 63.2(SD = 11.2) | 70.6(SD = 9.3) | < 0.001 |
Obesity | 39.6(285) | 22.3(114) | 81.4(171) | < 0.001 |
BMI(kg/m2) | 29.1(SD = 5.2) | 27.7(SD = 4.6) | 32.1(SD = 5.2) | < 0.001 |
FEMALES | 27.9(SD = 6.0) | 27.5(SD = 5.4) | 33.5(SD = 4.9) | < 0.001 |
MALES | 27.7(SD = 4.7) | 27.1(SD = 3.9) | 28.7(SD = 5.3) | < 0.001 |
Abdominal circumference(cm) | 100.7(SD = 11.7) | 95.8(SD = 13.0) | 107.2(SD = 13.8) | < 0.03 |
Blood pressure | 48.9(352) | 36.1(184) | 80.0(168) | < 0.001 |
BPS(mmHg) | 132.0(SD = 17.6) | 130.3(SD = 19.4) | 142.0(SD = 18.7) | < 0.001 |
FEMALES | 131.6(SD = 20.7) | 127.4(SD = 19.3) | 140.4(SD = 17.8) | < 0.001 |
MALES | 133.4(SD = 18.1) | 129.1(SD = 16.3) | 145.6(SD = 18.7) | < 0.001 |
BPD(mmHg) | 78.1(SD = 11.6) | 78.4(SD = 11.7) | 82.4(SD = 11.1) | < 0.001 |
FEMALES | 78.5(SD = 11.7) | 76.4(SD = 11.1) | 81.6(SD = 10.5) | < 0.001 |
MALES | 79.6(SD = 11.6) | 79.0(SD = 11.0) | 83.7(SD = 11.6) | < 0.001 |
Diabetes mellitus | 19.7(142) | 8.8(45) | 60.5(127) | < 0.001 |
Baseline glycemia(mg/dL) | 106.7(SD = 38.7) | 102.1(SD = 31.7) | 127.4(SD = 55.8) | < 0.001 |
FEMALES | 111.4(SD = 42.3) | 97.3 (SD = 27.5) | 139.4(SD = 51.8) | < 0.001 |
MALES | 114.8(SD = 46.0) | 103.6(SD = 41.0) | 133.5(SD = 48.1) | < 0.001 |
HbA1c;% | 5.6(SD = 1.5) | 5.4(SD = 1.3) | 6.2(SD = 2.0) | < 0.001 |
FEMALES | 6.04 (SD = 1.8) | 5.32(SD = 1.2) | 6.7(SD = 2.0) | < 0.001 |
MALES | 6.11(SD = 1.9) | 6.03(SD = 2.1) | 6.2(SD = 1.6) | < 0.001 |
Dyslipemia | 29.0(209) | 16.1(82) | 60.5(127) | < 0.001 |
Total cholesterol(mg/dL) | 219.2(SD = 40.1) | 217.3(SD = 42.5) | 226.6(SD = 46.3) | < 0.01 |
FEMALES | 219.6(SD = 41.5) | 215.4(SD = 44.2) | 239.7(SD = 52.6) | < 0.001 |
MALES | 218.5(SD = 43.9) | 217.9(SD = 43.9) | 223.5(SD = 42.8) | < 0.01 |
LDL-cholesterol(mg/dL) | 141.3(SD = 36.3) | 140.9(SD = 35.9) | 143.2(SD = 36.7) | NS |
FEMALES | 141.2(SD = 36.1) | 139.8(SD = 36.3) | 141.7(SD = 36.5) | NS |
MALES | 145.2(SD = 37.2) | 143.3(SD = 35.8) | 147.2(SD = 39.4) | NS |
HDL-cholesterol(mg/dL) | 54.4(SD = 19.0) | 54.0(SD = 16.6) | 50.8(SD = 17.4) | < 0.001 |
FEMALES | 53.2(SD = 18.2) | 58.7(SD = 18.4) | 52.4(SD = 16.1) | < 0.001 |
MALES | 50.9(SD = 22.3) | 52.2(SD = 20.6) | 50.1(SD = 20.8) | NS |
Triglycerides(mg/dL) | 151.4(SD = 109.6) | 147.0(SD = 107.0) | 165.4(SD = 118.3) | < 0.001 |
FEMALES | 134.0(SD = 79.2) | 104.4(SD = 59.2) | 177.5(SD = 87.1) | < 0.001 |
MALES | 174.0(SD = 135.7) | 148.0 (SD = 123) | 210.5(SD = 146.2) | < 0.002 |
Microalbuminuria(mg/d) | 38.3(SD = 131.2) | 18.2(SD = 64.1) | 103.8(SD = 233) | < 0.002 |
FEMALES | 17.8(SD = 42.3) | 13.7(SD = 18.2) | 24.5(SD = 64.1) | < 0.001 |
MALES | 65.5(SD = 191.3) | 42.5(SD = 112.4) | 101.7(SD = 269) | < 0.001 |
CVD risk(% at 10 years) | 13.8(SD = 10.0) | 13.4(SD = 8.3) | 23.8(SD = 10.0) | < 0.001 |
FEMALES | 8.7(SD = 7.9) | 6.5(SD = 5.3) | 17.3(SD = 10.0) | < 0.001 |
MALES | 19.7(SD = 11.1) | 14.4(SD = 9.8) | 26.4(SD = 11.6) | < 0,001 |
REGICOR(% at 10 years) | 8.8(SD = 9.8) | 7.2(SD = 8.9) | 10.7(SD = 9.5) | < 0.001 |
FEMALES | 3.7(SD = 5.3) | 2.9(SD= 4.7) | 5.6(SD = 7.1) | < 0.001 |
MALES | 10.1(SD = 8.8) | 8.2(SD = 9.0) | 13.5(SD = 9.4) | < 0.001 |
CVD complications | 19.7(142) 113 individuals | 11.0(56) 55 individuals | 40.9(86) 58 individuals | < 0.001 |
Cerebrovascular | 3.3(24) | 2.3(12) | 5.7(12) | < 0.001 |
Coronary | 4.2(30) | 2.9(15) | 7.1(15) | < 0.001 |
Peripheral vascular | 4.9(35) | 3.3(17) | 8.6(18) | < 0.001 |
Retinopathy | 2.5(18) | 1.4(7) | 5.2(11) | < 0.02 |
Nephropathy | 4.0(29) | 0.8(4) | 11.9(25) | < 0.001 |
Neuropathy | 0.8(6) | 0.2(1) | 2.4(5) | < 0.001 |
The data are expressed in percentages (absolute values) and mean (SD:standard deviation). BPS = systolic blood pressure; BPD = diastolic blood pressure; BMI = body mass index; CVD = cardiovascular disease risk according to the Framingham predictive equation; REGICOR: cardiovascular disease risk tables based on the Framingham equations and calibrated for Spain; NS = not significant