Table 2.
Characteristics Of Women With Normal Or Abnormal Follow Up Cytologic Smears Following LLETZ, Chris Hani Baragwanath Hospital, 2003 – 2006.
|
Abnormal* (n = 285) |
Normal* (n = 290) |
p-value | |
| Age, mean (sd) | 35.1 (8.0) | 37.5 (8.9) | 0.001 |
| Parity, mean (sd) | 2.7 (1.02) | 2.98 (0.97) | 0.004 |
| Contraceptive method, n (%) reporting use | |||
| Norethisterone oenanthate | 32 (11.2) | 43 (14.8) | 0.200 |
| Depomedroxyprogesterone acetate | 29 (10.2) | 48 (16.6) | 0.025 |
| Intra-uterine contraceptive device | 3 (1.1) | 4 (1.4) | 0.721 |
| Progestogen-only pill | 3 (1.1) | 7 (2.4) | 0.212 |
| Combined oral contraceptive | 20 (7.0) | 26 (9.0) | 0.389 |
| Sterilization | 9 (3.2) | 19 (6.6) | 0.059 |
| HIV status, n (%) self-reporting status | <0.0001 | ||
| Negative | 37 (13.0) | 112 (38.6) | |
| Positive | 184 (64.6) | 82 (28.3) | |
| Unknown | 64 (22.5) | 96 (33.1) | |
| CD4, n (%) | <0.0001 | ||
| <200 | 91 (55.5) | 23 (31.1) | |
| 200 – 499 | 59 (36.0) | 33 (44.6) | |
| >499 | 14 (8.5) | 18 (24.3) | |
| On antiretroviral therapy | 68 (23.86) | 21 (7.24) | <0.0001 |
| Baseline smear result, n (%) | 0.947 | ||
| H SIL | 216 (75.8) | 196 (67.6) | |
| L SIL | 34 (11.9) | 33 (11.4) | |
| ASCUS | 12 (4.2) | 12 (4.1) | |
| Histology of excised transformation zone, n (%) | 270 | 255 | 0.139 |
| Normal | 6 (2.2) | 7 (2.8) | |
| CIN I | 18 (6.8) | 28 (11.3) | |
| CIN II | 116 (43.9) | 90 (36.3) | |
| CIN III | 129 (48.9) | 126 (50.8) | |
| Microinvasion | 1 (0.4) | 4 (1.6) | |
| Presence of dysplasia at the margin of excised transformation zone | 253 | 243 | <0.0001 |
| Both | 35 (13.8) | 14 (5.8) | |
| Ectocervical | 84 (33.2) | 46 (18.9) | |
| Endocervical | 35 (13.8) | 35 (14.4) | |
| Margins clear | 99 (39.1) | 148 (60.9) |
* Numbers in each category may not sum to the total for the column owing to missing values.