Table 4.
Logistic regression assessing associations with persistence of abnormal smears following LLETZ: restricted to HIV-infected women (n = 196).
|
Univariate Odds Ratio (95% CI) |
Multivariate Odds Ratio (95%CI) |
p-value | |
| CD4 category (cells/mm3) | |||
| <200 | Referent | Referent | - |
| 200–499 | 0.45 (0.24 – 0.85) | 0.4 (0.2–0.8) | 0.017 |
| ≥500 | 0.2 (0.085 – 0.45) | 0.1 (0.01–0.2) | 0.000 |
| Disease at excision margins | |||
| Margins not involved | Referent | Referent | - |
| Ectocervical margin positive | 1.7 (0.93 – 3.3) | 2.0 (0.9–4.6) | 0.089 |
| Endocervical margin positive | 2.2 (0.8 – 5.8) | 5.6 (1.3–24.8) | 0.024 |
| Both endo- and ectocervical margins involved | 2.5 (0.86 – 7.1) | 4.3 (0.9–19.2) | 0.059 |
| Histology of excised transformation zone | |||
| CIN1 | Referent | Referent | - |
| CIN2 | 2.1 (0.8 – 5.3) | 2.5 (0.8–7.8) | 0.116 |
| CIN3 | 2.5 (0.96 – 6.4) | 3.8 (1.1–13.1) | 0.037 |