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Study 2 – Adjusted mean change from baseline to endpoint in HbA1c after 24 weeks of treatment with vildagliptin (50 mg bid) or placebo in metformin-treated patients with T2DM (p < 0.001) (Bosi et al 2007a).
Study 3 – Adjusted mean change from baseline to endpoint in HbA1c after 24 weeks of treatment with vildagliptin (50 mg bid) or pioglitazone (30 mg qd) in metformin-treated patients with T2DM; the between group difference was 0.10 ± 0.08% (95 CI: −0.05, −0.26) (Bolli et al 2008).
