Fig. 1.

Characterization of A-ob/ob, ob/ob, A-ob/+, and ob/+ mice. Body weight (g) of chow-fed female (A) and male (B) A-ob/ob, ob/ob, A-ob/+, and ob/+ mice from 4–20 weeks of age. Each data point represents mean and standard error of 9–18 mice per genotype. C: Cholesterol distribution among fast-protein liquid chromatograph-fractionated lipoproteins of serum obtained from 20-week-old ob/ob (black triangles) and A-ob/ob (black circles) mice. Serum from four animals per genotype was pooled. FPLC, fast-protein liquid chromatography.