Table 4.

Mutations (rpoB) fully explain growth advantage

Mutation	Selected rpoB mutant			Constructed rpoB mutant
	Median CI	(Dev)†	N‡	Median CI	(Dev.)†	N‡
Q513H	12.9	(5.9)	15	5.5	(10)	16
R529S	40.6	(45)	12	73.9	(100)	11
P564L	27.8	(93.2)	11	42.3	(18.4)	16

*P values (CI of mutant significantly different from CI of wild type by Mann–Whitney nonparametric test) were <0.0001 for all competitions.

^†Dev. is the absolute average deviation from the median (see Materials and Methods). Note: the CI was positive for all competitions.

^‡N is the number of independent colony competitions for each mutant.