Table 4.
Mutation | Selected rpoB mutant |
Constructed rpoB mutant |
||||
---|---|---|---|---|---|---|
Median CI | (Dev)† | N‡ | Median CI | (Dev.)† | N‡ | |
Q513H | 12.9 | (5.9) | 15 | 5.5 | (10) | 16 |
R529S | 40.6 | (45) | 12 | 73.9 | (100) | 11 |
P564L | 27.8 | (93.2) | 11 | 42.3 | (18.4) | 16 |
*P values (CI of mutant significantly different from CI of wild type by Mann–Whitney nonparametric test) were <0.0001 for all competitions.
†Dev. is the absolute average deviation from the median (see Materials and Methods). Note: the CI was positive for all competitions.
‡N is the number of independent colony competitions for each mutant.