Table 4.
Asymmetric dihydroxylation of (E,Z)-dienoates
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|---|---|---|---|
| Entry | Ligand | Yield% (17) | ee%b |
| 1 | (DHQ)2PHAL | 63 | 56 |
| 2 | (DHQD)2PHAL | 35 | 70 |
| 3 | DHQ-4-Me-2-Quin | 50 | 49 |
| 4 | (DHQD)2PYR | 64 | 73 |
| 5 | DHQD-9-phen | 47 | 64 |
| 6 | (DHQD)2AQN | 35 | 61 |
| 7 | DHQD-4-CLB | 38 | 30 |
a) 17 is major from DHQD ligands whereas (ent)-17 is major from DHQ ligands.
ee% were determined by chiral HPLC
