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. 2008 Feb;4(1):209–218. doi: 10.2147/ndt.s2059

Figure 3.

Figure 3

Effects of DHEA, DHEA-S, and pregnenolone on [Ca2+]i increase induced by AβP. A. After a 20-min incubation period at 37 °C in 25 μM DHEA-S, DHEA, and pregnenolone (PG), the average increase in [Ca2+]i induced by 20 μM AβP[25–35] was determined. As a control, the same DMSO concentration (0.5%) was added to the cultured neurons by the same protocol. Data are expressed as mean ± SEM, n = 200, ** p < 0.001. B. Percentage of cells responding to AβP under same conditions as those in (A). Data are expressed as mean ± SEM, n = 5.