Table 4.
Sample and study design features, and ADHD symptom specific outcome measures, of 3 randomized, controlled studies of psychotherapy in adult ADHD
Authors | N | Rank ofa current comorbidity | Length of study | Type of psychotherapy | Efficacy; physician rated responseb | Efficacy; patient rated responseb | ||
---|---|---|---|---|---|---|---|---|
Safren 2005 | 31 | Low | 15 weeks | Cognitive Behavioural Therapy(CBT) + continued medication All patients on medication |
Effect size 1.2–1.4 Responders: CBT 56% Control 13% |
Effect size 1.7 | ||
Stevenson 2002 | 43 | Low | 8 weeks + 2 and 12 months follow-up | Cognitive Remediation Programme (CRP) + continued medication Med. 22 Not med. 21 |
Responders: Post treatment 36% 2 months 55% 12 months: 50% Effect size 1.4 |
|||
Stevenson 2003 | 35 | Low | 8 weeks + 2 months follow-up | Psychosocial self-directed intervention + continued medication Med. 23 Not med. 12 |
Responders: Post treatment 47% 2 months 36% |
The study was ranked as low in current comorbidity if there was no or very sparse information on comorbidity, only lifetime comorbidity presented, or low numbers of comorbid disorders like anxiety and mood disorders only. The study was ranked as moderate in current comorbidity if the sample had more than 25% current comorbidity on major depression, substance abuse or alcohol abuse, and/or personality disorders. Studies presenting more than 75% current comorbidity on major depression, substance abuse or alcohol abuse, and/or personality disorders were ranked as high comorbidity.
When available the measures presented are response rates defined as percent of patients experiencing >30% reduction of ADHD symptoms on an ADHD rating scale, and/or much or very much improved on Clinical Global Impression-Improvement (CGI-I). If this definition was not used, we present the response rates as defined by the paper, or effect size (computed by taking the mean outcome score of active treatment minus the mean outcome score of control/placebo and dividing the result by the pooled standard deviation).