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. 2008 Aug;179(4):2253–2261. doi: 10.1534/genetics.107.077719

TABLE 2.

Effect of varying b, the background risk, in the threshold model

b p PAR OR1 OR2 KM λ1
10−6 0.199 0.08 1.46 2.09 0.13 4.6
10−5 0.199 0.08 1.46 2.08 0.13 4.5
10−4 0.198 0.08 1.45 2.08 0.13 4.4
10−3 0.197 0.08 1.41 1.98 0.12 4.0

In all cases, L = 70, T = 22, σe = 2.5, h = 0.5, and p is adjusted so that K = 0.01. All results are based on the averages of 106 replicates of the simulation program described in the text.