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. 2008 Aug 25;3(8):e3050. doi: 10.1371/journal.pone.0003050

Figure 5. Pro and anti-inflammatory molecules expression after B1R antagonist and agonist treatment.

Figure 5

All molecule expressions were estimated by real-time PCR at 24 hours of reperfusion. B1R antagonism (R-954) resulted in lower pro-inflammatory molecule expression (T-bet, IL-1β and MCP-1) (A, B and C) and higher anti-inflammatory response (GATA-3, IL-4, IL-10 and HO-1) (D, E, F and G). Molecule expression after B1R agonism (DABK) were similar to non-treated mice. Statistical analyses were performed using ANOVA.*IR+HOE-140 versus IR, p<0.05.