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Comparison of the kinetics of isotope exchange. The concentrations of [D2] and [HD] are plotted as plain and dashed lines, respectively. The experiments were started by adding the enzyme at t = 0. pH 7, T = 30°C, enzyme concentration 2.7 μg/ml (WT), 5.6 μg/ml (FI), and 7.1 μg/ml (MM).
