Skip to main content
. 2008 Aug 7;105(32):11364–11369. doi: 10.1073/pnas.0802076105

Fig. 1.

Fig. 1.

Normal ultrastructure but increased numbers of larger mitochondria in the striatum of PINK1−/− mice. (A) Absence of gross ultrastructural defects in mitochondria of the PINK1−/− striatum at 3–4 (upper panels) and 24 (lower panels) months. Arrows indicate the presence of clearly defined and intact cristae. Asterisks show the presence of outer membranes. (B) Distribution of mitochondria in different size bins reveals increased numbers of larger mitochondria in the PINK1−/− striatum at 3–4 and 24 months (*, P < 0.05). (C) Western blot analysis of mitochondrial marker proteins shows normal levels of porin (for outer membrane), AIF (for intermembrane space), Complex V (CxV for inner membrane) and ICDH (for matrix) in the PINK1−/− striatum. Bands shown are representative of a total of 4 samples per genotype.