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. 2008 Aug 21;3(8):e3026. doi: 10.1371/journal.pone.0003026

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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(A) Streptokinase, (B) GAPDH, and (C) Enolase. Inferred products for each of the virulence factors implicated in PSGN pathogenesis were aligned and relationships were inferred using the UPGMA method. GCS S. equi subsp. equi and zooepidemicus strains are shown in red, GAS S. pyogenes in blue, GBS S. agalactiae in green, GCS/GGS S. dysgalactiae subsp. equisimilis in purple, and other streptococcal species in black. These virulence factors are not more closely related between S. zooepidemicus and S. pyogenes than among the other streptococcal species.