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Improvement in the signal-to-noise ratio (S/N) of [M+H3]3+ for ESI of a 0.1 nM of neurotensin solution. a) Continuous regime. b) Trapping mode. Accumulation time = 100 ms, extraction time = 70 μs. In both the continuous and trapping modes the sample infusion rate was 60 nl/min and TOF acquisition time was 3 seconds.
