Table 1.

Molecules involved in body iron metabolism

Molecules for intestinal iron absorption

Divalent metal transporter 1 (DMT1)

Duodenal cytochrome b (Dcytb)

Heme carrier protein (HCP)

Hemeoxygenase-1

Ferroportin

Hephaestin

Transferrin

Molecules for bone marrow iron uptake

Transferrin receptor 1

Transferrin

Molecules for reutilization of senescent red blood cells

Hemeoxygenase-1

Ferroportin

Transferrin

Molecules for hepatic iron storage

Ferritin

Hemosiderin

Transferrin

Transferrin receptor 1

Transferrin receptor 2

Non-transferrin-bound iron

HFE

β2-microglobin

Divalent metal transporter 1

ZIP14

Hemojuvelin

Molecules for systemic iron regulation

Hepcidin

(Unknown erythroid regulator?)