Figure 4.

Effect of integrin antibodies on adhesion of SCg6 cells to ECM constituents. Adhesion assays on substrata coated with laminin (A), type IV collagen (B), fibronectin (C), or type I collagen (D) were performed for 1 h in the presence of increasing concentrations of antibodies against α1 (▵), α2 (•), α6 (▪), or β1 (○) integrin subunits. Results are normalized with the number of cells adhering to ECM substrata in the absence of antibodies set to 100. Means ± SD from three independent experiments are shown.