TABLE 1.
Cytokine Analysis for ATRA-Treated HL-60 Cellsa
| Day/cytokine
|
No treatment
|
ATRA-treated
|
||
|---|---|---|---|---|
| Day 2 | Day 4 | Day 2 | Day 4 | |
| IL-1β (IL1B) | 72 (27) | 107 (25) | 202 (29) | – |
| IL-7 (IL7) | 46 (50) | 42 (58) | – | – |
| IL-8 (IL8) | 182 (8) | 78 (4) | 156 (8) | 133 (3) |
| IL-15 (IL15) | – | 21 (4) | 19 (42) | – |
| IL-17 (IL17) | 7 (8) | 13 (20) | 12 (14) | – |
| TNF-α (TNF) | 20 (0) | – | – | – |
| MIP-1α (CCL3) | – | 41 (28) | 34 (35) | 30 (20) |
| MIP-1β (CCL4) | – | – | 713 (4) | – |
| MIG (CXCL9) | 32 (35) | – | – | – |
| RANTES (CCL5) | 314 (3) | 200 (6) | 135 (34) | – |
| MCP-1 (CCL2) | 10 (8) | 7 (12) | 149 (3) | 57 (5) |
| IP-10 (CXCL10) | 18 (6) | 17 (18) | 20 (36) | 8 (139) |
a
All values in pg/ml analyzed in triplicate (±sd). –, Values below detectable limit of assay. MIG, Monokine induced by IFN-γ; IP-10, IFN-inducible protein 10.