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. Author manuscript; available in PMC: 2009 Jan 1.
Published in final edited form as: Nutr Res. 2008;28(5):285–292. doi: 10.1016/j.nutres.2008.02.013

Figure 1. Brain lesions seen on magnetic resonance imaging (MRI)1.

Figure 1

1Lesions, believed to be of ischemic origin, occur with aging but particularly with late-life depression. These lesions may damage mood regulation pathways (leading to depression) or cause cognitive impairment. Lesions are shown here on a proton density image (left), fluid-attenuated inversion recovery (FLAIR) image (center), and tissue classification image (right). Lesions are red on tissue classification image. Images are courtesy of the Neuropsychiatric Imaging Research Laboratory at Duke University.