TABLE 1.
ΔF/F – V parameters and electrically-evoked contractions The parameters for ΔF/F – V were obtained by best fits of the raw data according to Equation 2. The values are given as the means ± S.E., with the number of myotubes tested indicated in parentheses. ND, not determined.
|
Construct
|
ΔF/F – V
|
Contracting cells/tested
|
||
|---|---|---|---|---|
| ΔF/Fmax | VF | kF | ||
| ΔF/F | mV | mV | ||
| GFP-α1S | 0.75 ± 0.16 (5) | 8.1 ± 2.1 | 7.1 ± 2.1 | 22/39c |
| GFP-α1S[III-IVa] | 0.27 ± 0.09 (5)a | –2.0 ± 1.9b | 8.1 ± 1.1 | 10/16 |
| Uninjected dysgenic myotubes | ND | 0/91 | ||
a
Significant difference from GFP-α1S (p < 0.05)
b
Significant difference from GFP-α1S (p < 0.01)
c
Data from Ref. 24