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. 2008 Aug 1;4:31. doi: 10.1186/1744-8069-4-31

Figure 2.

Figure 2

Dose-response curves for ICV injection of ZJ43, 2-PMPA and NAAG representing the cumulative instances of formalin evoked flinches during the phase 1 (a) and the phase 2 (b). ZJ43, 2-PMPA and NAAG reduced the number of phase 1 and the phase 2 flinching behaviors in a dose dependent manner. Each point represents the group mean and S.E.M. of responses by groups of 5–6 rats. * <0.05 and ** <0.005 versus rats given saline ICV prior to formalin-induced inflammation.