Table 1.

Targeted sites for design^a

M13 variable residues
K R R W K K N F I A V S A A N R F K K I S S S G A L
+ + + + +
		CaM contact residues
M13 Site		Variable	Nearby Unvaried
+	2	E127	M124
	4	F92 I100 L105 I125	M109 M124 A128 V136 M144 M145
+	5	E11	M145
+	6	E14	L18
	11	L39 V91 L112	A88 F92
+	16	E84	M71 M72
	17	I27 V55 I63	L32 M36 M51 I52 M71
+	19	S81 E83 E87	E84

^aSeveral individual M13 positions were varied in combination with the closest contacting residues on CaM: + indicates an M13 basic residue; indicates a hydrophobic anchor point. All CaM residues with any side-chain heavy atom within 6.0 Å of any M13 side-chain heavy atom in the group are listed.